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Extended-time period Unwanted side effects are unlikely for rare consumers of modest amounts of cannabis. Persistent use of cannabis — particularly when started out being an adolescent — could potentially cause cognitive impairment later in life and improve the probability of addiction, which occurs in roughly one in ten those who use cannabis.

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These outcomes, together with a prior report showing that a small-molecule ACKR3 agonist CCX771 exhibits anxiolytic-like actions in mice,2 aid the notion of focusing on ACKR3 as a singular strategy to modulate the opioid procedure, which could open new therapeutic avenues for opioid-connected disorders.Morphine and various opioids raise the action

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